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1. Leptin is regarded as an indicator of long-term energy stores. Identify the TRUE statement about leptin levels in humans. A. Subcutaneous fat is the main source of leptin. B. Leptin is higher in obese type 2 diabetes patients compared to patients with obesity without diabetes. C. Leptin levels are inversely correlated with insulin in obese patients with insulin resistance. D. Low leptin levels induce negative energy balance.